CPC technology class · C12

C12M — Apparatus FOR Enzymology OR Microbiology

Apparatus for enzymology or microbiology; apparatus for culturing microorganisms for producing biomass, for growing cells or for obtaining fermentation or metabolic products, i.e. bioreactors or fermenters. 8,154 US utility patents granted 2015–2025, with the leading assignees and year-by-year filing trajectory.

8,154
US patents granted
C12
Parent CPC class
20
Active assignees
+64%
5-yr velocity
Top assignee: Life Technologies Corporation (110 patents)

CPC subclass C12M — APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS — covers 8,154 US utility patents granted between 2015 and 2025 according to USPTO PatentsView records. This subclass sits within the broader CPC class C12 (BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING), one of roughly 250 top-level technology categories in the Cooperative Patent Classification system jointly maintained by the USPTO and the European Patent Office. At the subclass level, four-character codes like C12M give the most practical resolution for tracking a specific technology domain without losing sight of adjacent filings. Every grant here has been classified by a USPTO examiner based on the technical disclosure in the patent specification.

The competitive landscape in C12M is shaped by 20 distinct companies actively filing in this space. Life Technologies Corporation leads with 110 patents, followed by Sartorius Stedim Biotech GmbH at 237 grants and Global Life Sciences Solutions USA LLC at 111. Concentration at the top of the leaderboard indicates whether this technology area is dominated by a handful of incumbents or fragmented across many filers — a useful signal for investors evaluating competitive moats and for product teams mapping freedom-to-operate risk.

Filing trajectory matters as much as static counts. The yearly series on this page plots grants from 2015 through 2025, highlighting whether innovation in C12M is accelerating, plateauing, or cooling. Technology areas with rising post-2020 activity often reflect emerging markets or new platform shifts, while declining filings can signal mature domains where incremental improvement has slowed. Researchers, licensing professionals, and competitive-intelligence teams use these patterns — together with the top-assignee distribution — to decide where to invest, where to license, and where to avoid entanglement. All counts on this page come directly from USPTO PatentsView and reflect US granted utility patents only.

Is C12M innovation accelerating?

US utility-patent grants per year in C12M, 2015–2025 — recent five years are up 64% versus 2015–2019.

4005006007008009001,000 20152016201720182019202020212022202320242025 673

Who leads C12M?

The 12 most active assignees in APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS — wider bars mean more grants

patents

What this shows Life is the most active filer in C12M, holding 110 of the 8,154 patents in this class. Concentration at the top signals how contestable this technology area is for new entrants.

Source USPTO PatentsView — granted utility patents As of 2015–2025 grant years
View data table

About This Class

CPC subclass C12M belongs to class C12.

8,154 patents were granted in this class between 2015 and 2025.

20 companies actively patent in this space.

Classification System

Cooperative Patent Classification (CPC) is a hierarchical patent classification system used by the USPTO and EPO.

Frequently Asked Questions

What is CPC class C12M?
CPC subclass C12M covers APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS. It belongs to CPC class C12 (BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING). The Cooperative Patent Classification is a hierarchical system used by the USPTO and European Patent Office to categorize patents by technology.
How many patents have been filed in C12M?
8,154 US utility patents were granted in CPC subclass C12M between 2015 and 2025, based on USPTO PatentsView data.
Which company holds the most patents in C12M?
Life Technologies Corporation leads C12M with 110 patents, making it the most active assignee in this technology area.
How is patent data for C12M collected?
Patent data comes from USPTO PatentsView, a public research dataset maintained by the United States Patent and Trademark Office. It covers all US granted utility patents and assigns CPC codes based on the technology described in each patent.
What is the difference between CPC class and subclass?
A CPC class (e.g., C12) is a broad technology category. Subclasses like C12M provide finer granularity within that category. PlainPatent organizes data at the subclass level (4-character codes) for the most useful view of technology domains.

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Explore the patent dataset

Data sourced from USPTO PatentsView — official U.S. government patent data. See our methodology for computation details. Retrieved and formatted by PlainPatent Editorial