CPC technology class · C12
C12M — Apparatus FOR Enzymology OR Microbiology
Apparatus for enzymology or microbiology; apparatus for culturing microorganisms for producing biomass, for growing cells or for obtaining fermentation or metabolic products, i.e. bioreactors or fermenters. 8,154 US utility patents granted 2015–2025, with the leading assignees and year-by-year filing trajectory.
- 8,154
- US patents granted
- C12
- Parent CPC class
- 20
- Active assignees
- +64%
- 5-yr velocity
CPC subclass C12M — APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS — covers 8,154 US utility patents granted between 2015 and 2025 according to USPTO PatentsView records. This subclass sits within the broader CPC class C12 (BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING), one of roughly 250 top-level technology categories in the Cooperative Patent Classification system jointly maintained by the USPTO and the European Patent Office. At the subclass level, four-character codes like C12M give the most practical resolution for tracking a specific technology domain without losing sight of adjacent filings. Every grant here has been classified by a USPTO examiner based on the technical disclosure in the patent specification.
The competitive landscape in C12M is shaped by 20 distinct companies actively filing in this space. Life Technologies Corporation leads with 110 patents, followed by Sartorius Stedim Biotech GmbH at 237 grants and Global Life Sciences Solutions USA LLC at 111. Concentration at the top of the leaderboard indicates whether this technology area is dominated by a handful of incumbents or fragmented across many filers — a useful signal for investors evaluating competitive moats and for product teams mapping freedom-to-operate risk.
Filing trajectory matters as much as static counts. The yearly series on this page plots grants from 2015 through 2025, highlighting whether innovation in C12M is accelerating, plateauing, or cooling. Technology areas with rising post-2020 activity often reflect emerging markets or new platform shifts, while declining filings can signal mature domains where incremental improvement has slowed. Researchers, licensing professionals, and competitive-intelligence teams use these patterns — together with the top-assignee distribution — to decide where to invest, where to license, and where to avoid entanglement. All counts on this page come directly from USPTO PatentsView and reflect US granted utility patents only.
Is C12M innovation accelerating?
US utility-patent grants per year in C12M, 2015–2025 — recent five years are up 64% versus 2015–2019.
Who leads C12M?
The 12 most active assignees in APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS — wider bars mean more grants
- Life
Life Technologies Corporation
1,296 patents
- Sartorius Stedim Biot… 237
Sartorius Stedim Biotech GmbH
237 patents
- Global Life Sciences… 111
Global Life Sciences Solutions USA LLC
111 patents
- President and Fellows…
President and Fellows of Harvard College
1,824 patents
- Inscripta 165
Inscripta Inc.
165 patents
- Flodesign Sonics 83
FloDesign Sonics, Inc.
83 patents
- Emulate 77
EMULATE, INC.
77 patents
- Emd Millipore 287
EMD Millipore Corporation
287 patents
- Xyleco 166
XYLECO, INC.
166 patents
- Biomerieux 255
BIOMERIEUX, INC.
255 patents
- Terumo Bct 116
Terumo BCT, Inc.
116 patents
- Nikon
NIKON CORPORATION
2,316 patents
What this shows Life is the most active filer in C12M, holding 110 of the 8,154 patents in this class. Concentration at the top signals how contestable this technology area is for new entrants.
View data table
| Rank | Company | Patents in C12M |
|---|---|---|
| #1 | Life Technologies Corporation | 1,296 |
| #2 | Sartorius Stedim Biotech GmbH | 237 |
| #3 | Global Life Sciences Solutions USA LLC | 111 |
| #4 | President and Fellows of Harvard College | 1,824 |
| #5 | Inscripta Inc. | 165 |
| #6 | FloDesign Sonics, Inc. | 83 |
| #7 | EMULATE, INC. | 77 |
| #8 | EMD Millipore Corporation | 287 |
| #9 | XYLECO, INC. | 166 |
| #10 | BIOMERIEUX, INC. | 255 |
| #11 | Terumo BCT, Inc. | 116 |
| #12 | NIKON CORPORATION | 2,316 |
| #13 | GE Healthcare Bio-Science AB | 258 |
| #14 | Becton, Dickinson and Company | 2,235 |
| #15 | Repligen Corporation | 68 |
| #16 | BD KIESTRA B.V. | 53 |
| #17 | CYTIVA SWEDEN AB | 139 |
| #18 | The Charles Stark Draper Laboratory, Inc. | 446 |
| #19 | Toyo Seikan Co., Ltd. | 333 |
| #20 | Shimadzu Corporation | 2,128 |
About This Class
CPC subclass C12M belongs to class C12.
8,154 patents were granted in this class between 2015 and 2025.
20 companies actively patent in this space.
Classification System
Cooperative Patent Classification (CPC) is a hierarchical patent classification system used by the USPTO and EPO.
Frequently Asked Questions
What is CPC class C12M?
How many patents have been filed in C12M?
Which company holds the most patents in C12M?
How is patent data for C12M collected?
What is the difference between CPC class and subclass?
Learn More
Explore the patent dataset
Read our methodology — how this data is sourced, computed, and verified.