CPC technology class · C12

C12N — Microorganisms OR Enzymes

Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media. 68,530 US utility patents granted 2015–2025, with the leading assignees and year-by-year filing trajectory.

68,530
US patents granted
C12
Parent CPC class
20
Active assignees
+23%
5-yr velocity
Top assignee: Monsanto Technology LLC (1,335 patents)

CPC subclass C12N — MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA — covers 68,530 US utility patents granted between 2015 and 2025 according to USPTO PatentsView records. This subclass sits within the broader CPC class C12 (BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING), one of roughly 250 top-level technology categories in the Cooperative Patent Classification system jointly maintained by the USPTO and the European Patent Office. At the subclass level, four-character codes like C12N give the most practical resolution for tracking a specific technology domain without losing sight of adjacent filings. Every grant here has been classified by a USPTO examiner based on the technical disclosure in the patent specification.

The competitive landscape in C12N is shaped by 20 distinct companies actively filing in this space. Monsanto Technology LLC leads with 1,335 patents, followed by The Regents of the University of California at 6,428 grants and Novozymes A/S at 770. Concentration at the top of the leaderboard indicates whether this technology area is dominated by a handful of incumbents or fragmented across many filers — a useful signal for investors evaluating competitive moats and for product teams mapping freedom-to-operate risk.

Filing trajectory matters as much as static counts. The yearly series on this page plots grants from 2015 through 2025, highlighting whether innovation in C12N is accelerating, plateauing, or cooling. Technology areas with rising post-2020 activity often reflect emerging markets or new platform shifts, while declining filings can signal mature domains where incremental improvement has slowed. Researchers, licensing professionals, and competitive-intelligence teams use these patterns — together with the top-assignee distribution — to decide where to invest, where to license, and where to avoid entanglement. All counts on this page come directly from USPTO PatentsView and reflect US granted utility patents only.

Is C12N innovation accelerating?

US utility-patent grants per year in C12N, 2015–2025 — recent five years are up 23% versus 2015–2019.

4,0004,5005,0005,5006,0006,500 20152016201720182019202020212022202320242025 4,463

Who leads C12N?

The 12 most active assignees in MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA — wider bars mean more grants

patents

What this shows Monsanto Technology is the most active filer in C12N, holding 1,335 of the 68,530 patents in this class. Concentration at the top signals how contestable this technology area is for new entrants.

Source USPTO PatentsView — granted utility patents As of 2015–2025 grant years
View data table

About This Class

CPC subclass C12N belongs to class C12.

68,530 patents were granted in this class between 2015 and 2025.

20 companies actively patent in this space.

Classification System

Cooperative Patent Classification (CPC) is a hierarchical patent classification system used by the USPTO and EPO.

Frequently Asked Questions

What is CPC class C12N?
CPC subclass C12N covers MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA. It belongs to CPC class C12 (BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING). The Cooperative Patent Classification is a hierarchical system used by the USPTO and European Patent Office to categorize patents by technology.
How many patents have been filed in C12N?
68,530 US utility patents were granted in CPC subclass C12N between 2015 and 2025, based on USPTO PatentsView data.
Which company holds the most patents in C12N?
Monsanto Technology LLC leads C12N with 1,335 patents, making it the most active assignee in this technology area.
How is patent data for C12N collected?
Patent data comes from USPTO PatentsView, a public research dataset maintained by the United States Patent and Trademark Office. It covers all US granted utility patents and assigns CPC codes based on the technology described in each patent.
What is the difference between CPC class and subclass?
A CPC class (e.g., C12) is a broad technology category. Subclasses like C12N provide finer granularity within that category. PlainPatent organizes data at the subclass level (4-character codes) for the most useful view of technology domains.

Learn More

Explore the patent dataset

Data sourced from USPTO PatentsView — official U.S. government patent data. See our methodology for computation details. Retrieved and formatted by PlainPatent Editorial