CPC technology class · C12
C12Y — Enzymes
Enzymes. 17,214 US utility patents granted 2015–2025, with the leading assignees and year-by-year filing trajectory.
- 17,214
- US patents granted
- C12
- Parent CPC class
- 20
- Active assignees
- +22%
- 5-yr velocity
CPC subclass C12Y — ENZYMES — covers 17,214 US utility patents granted between 2015 and 2025 according to USPTO PatentsView records. This subclass sits within the broader CPC class C12 (BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING), one of roughly 250 top-level technology categories in the Cooperative Patent Classification system jointly maintained by the USPTO and the European Patent Office. At the subclass level, four-character codes like C12Y give the most practical resolution for tracking a specific technology domain without losing sight of adjacent filings. Every grant here has been classified by a USPTO examiner based on the technical disclosure in the patent specification.
The competitive landscape in C12Y is shaped by 20 distinct companies actively filing in this space. Novozymes A/S leads with 540 patents, followed by The Regents of the University of California at 6,428 grants and Codexis, Inc. at 350. Concentration at the top of the leaderboard indicates whether this technology area is dominated by a handful of incumbents or fragmented across many filers — a useful signal for investors evaluating competitive moats and for product teams mapping freedom-to-operate risk.
Filing trajectory matters as much as static counts. The yearly series on this page plots grants from 2015 through 2025, highlighting whether innovation in C12Y is accelerating, plateauing, or cooling. Technology areas with rising post-2020 activity often reflect emerging markets or new platform shifts, while declining filings can signal mature domains where incremental improvement has slowed. Researchers, licensing professionals, and competitive-intelligence teams use these patterns — together with the top-assignee distribution — to decide where to invest, where to license, and where to avoid entanglement. All counts on this page come directly from USPTO PatentsView and reflect US granted utility patents only.
Is C12Y innovation accelerating?
US utility-patent grants per year in C12Y, 2015–2025 — recent five years are up 22% versus 2015–2019.
Who leads C12Y?
The 12 most active assignees in ENZYMES — wider bars mean more grants
- Novozymes A/S 770
Novozymes A/S
770 patents
- The Regents of the Un…
The Regents of the University of California
6,428 patents
- Codexis 350
Codexis, Inc.
350 patents
- Dsm Ip Assets B V 1,027
DSM IP ASSETS B.V.
1,027 patents
- Novozymes 208
Novozymes, Inc.
208 patents
- President and Fellows… 1,824
President and Fellows of Harvard College
1,824 patents
- Danisco Us 213
Danisco US Inc.
213 patents
- Cj Cheiljedang 709
CJ CHEILJEDANG CORPORATION
709 patents
- Jiangnan University 511
Jiangnan University
511 patents
- Immatics Biotechnolog… 690
Immatics Biotechnologies GmbH
690 patents
- The Trustees of the U… 1,264
The Trustees of the University of Pennsylvania
1,264 patents
- Regeneron Pharmaceuti… 1,117
REGENERON PHARMACEUTICALS, INC.
1,117 patents
What this shows Novozymes A/S is the most active filer in C12Y, holding 540 of the 17,214 patents in this class. Concentration at the top signals how contestable this technology area is for new entrants.
View data table
| Rank | Company | Patents in C12Y |
|---|---|---|
| #1 | Novozymes A/S | 770 |
| #2 | The Regents of the University of California | 6,428 |
| #3 | Codexis, Inc. | 350 |
| #4 | DSM IP ASSETS B.V. | 1,027 |
| #5 | Novozymes, Inc. | 208 |
| #6 | President and Fellows of Harvard College | 1,824 |
| #7 | Danisco US Inc. | 213 |
| #8 | CJ CHEILJEDANG CORPORATION | 709 |
| #9 | Jiangnan University | 511 |
| #10 | Immatics Biotechnologies GmbH | 690 |
| #11 | The Trustees of the University of Pennsylvania | 1,264 |
| #12 | REGENERON PHARMACEUTICALS, INC. | 1,117 |
| #13 | Genomatica, Inc. | 155 |
| #14 | The General Hospital Corporation | 1,529 |
| #15 | The Board of Regents of the University of Texas System | 2,495 |
| #16 | Wisconsin Alumni Research Foundation | 1,659 |
| #17 | aTyr Pharma, Inc. | 82 |
| #18 | Baxalta Incorporated | 300 |
| #19 | CALIFORNIA INSTITUTE OF TECHNOLOGY | 1,842 |
| #20 | Life Technologies Corporation | 1,296 |
About This Class
CPC subclass C12Y belongs to class C12.
17,214 patents were granted in this class between 2015 and 2025.
20 companies actively patent in this space.
Classification System
Cooperative Patent Classification (CPC) is a hierarchical patent classification system used by the USPTO and EPO.
Frequently Asked Questions
What is CPC class C12Y?
How many patents have been filed in C12Y?
Which company holds the most patents in C12Y?
How is patent data for C12Y collected?
What is the difference between CPC class and subclass?
Learn More
Explore the patent dataset
Read our methodology — how this data is sourced, computed, and verified.