Where does Ionis Pharmaceuticals, Inc. rank among US patent assignees?

According to USPTO PatentsView (2015–2025 granted utility patents), Ionis Pharmaceuticals, Inc. ranks #1,536 of 49,997 assignees by granted-patent volume, the same sort as the companies listing and top-holders ranking. See /methodology/#corpus-placement.

How many patents does Ionis Pharmaceuticals, Inc. hold?

Ionis Pharmaceuticals, Inc. holds 271 US utility patents granted between 2016 and 2025, spanning 15 technology areas.

What is Ionis Pharmaceuticals, Inc.'s Innovation Score?

Ionis Pharmaceuticals, Inc. has an Innovation Score of 52.2 out of 100 (top 10% of the corpus). This composite metric weighs portfolio volume (40%), grant velocity (20%), technology breadth (25%), and claim depth (15%).

Is Ionis Pharmaceuticals, Inc.'s patent grant rate increasing or decreasing?

Ionis Pharmaceuticals, Inc.'s recent grant velocity is +11% compared to the prior five-year period (grant years, not application filing dates). The company is maintaining or growing its granted-patent output.

What does claim depth mean for Ionis Pharmaceuticals, Inc.'s patents?

Ionis Pharmaceuticals, Inc.'s patents average 22.9 claims each. This is an aggregate descriptive count from the grant record; it does not establish claim scope, legal strength, enforceability, or design-around risk.

How is the Ionis Pharmaceuticals, Inc. patent data sourced?

All patent data comes from USPTO PatentsView, a public research dataset maintained by the United States Patent and Trademark Office covering US granted utility patents from 2015 to 2025.

USPTO 2015–2025 USPTO PatentsView US Corporation

Ionis Pharmaceuticals, Inc.

Q: What technology areas does Ionis Pharmaceuticals, Inc. focus on?

Ionis Pharmaceuticals, Inc.'s top technology area is C12N (Microorganisms OR ENZYMES; Compositions THEREOF; Propagating, Preserving, OR Maintaining MICROORGANISMS; Mutation OR Genetic ENGINEERING; Culture Media) with 254 patents, ranking #22 of 4,144 assignees active in that subclass. Grants appear in 15 CPC subclasses total.

USPTO PatentsView assignee record - 271 granted patents across 15 technology areas, recorded in grant years 2016–2025. Grant-trend analysis is cross-referenced to USPTO Patent Public Search; it does not measure application filings, current R&D, or legal strength. Primary class: C12N (Microorganisms OR ENZYMES; Compositions THEREOF; Propagating, Preserving, OR Maintaining MICROORGANISMS; Mutation OR Genetic ENGINEERING; Culture Media).

Compiled by PlainPatent · May 15, 2026

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Explore the portfolio See the ranking

The verdict

According to USPTO PatentsView, Ionis ranks #1,536 of 49,997 tracked US assignees by granted-patent volume, with 271 patents across 15 technology areas.

#1,536
of 49,997 US assignees by volume: Top 10%
by Innovation Score (52.2/100): 22.9
avg claims per patent: +11%
grant velocity, last 5 yrs

USPTO PatentsView assignee plate

Corpus R1536 · US Corporation #1,536 · 271 grants

GRANTS-MID · TOP-DECILE · PHOTO-FINISH · CPC-FOCUS · INNOV-PAR · CLAIMS-DENSE · TYPE-USCORP · VEL-UP · BOOK-FULL

GRANTS-MID 271 grants
TOP-DECILE #1,536/49,997
PHOTO-FINISH Central Glass
CPC-FOCUS C12N · 15 areas
INNOV-PAR 52.2/100
CLAIMS-DENSE 22.9 claims/avg
TYPE-USCORP US Corporation
VEL-UP +11% vel
BOOK-FULL 10/10 fields

Nearest grant-volume peer: Central Glass Company, Limited (±0 grants)

Instrument codes from this assignee’s USPTO PatentsView grant sheet: volume band, corpus rank, photo-finish peer, lead CPC, Innovation Score, claim depth, assignee type, velocity, and book completeness. Not a USPTO rating of patent strength.

How Ionis’s 52.2 Innovation Score adds up

The same four weighted components behind every Innovation Score on PlainPatent: portfolio volume, grant velocity, technology breadth, and claim depth.

Volume 19.4 pts (37%) Velocity 5.4 pts (10%) Breadth 13.7 pts (26%) Claim depth 13.8 pts (26%)

Qualcomm Incorporated · highest

85
Carl Zeiss · near

52
Beijing Naura… · near

52
Darex · near

52
Ionis Pharmaceuticals · this assignee

52
RingCentral · near

52
3D Lighting… · lowest

7

What this shows Ionis's Innovation Score is 52.2/100 (top 10% of the PatentsView-derived corpus). The chart places that score against the nearest Innovation Score peers plus corpus poles, not a reprint of the volume ranking.

Does more volume mean deeper claims for Ionis?

Each dot is one of Ionis’s 8 nearest volume peers (same corpus rank neighbourhood as the chart above), placed by total granted patents (horizontal) against average claims per patent (vertical). Ionis’s own 22.9 claims/patent is ABOVE the 12.4 median for these volume peers. More thorough claims than most filers at this scale, not just more of them.

Ionis vs its 8 nearest volume peers: granted patents vs average claims per patent. Source: USPTO PatentsView.

Where Ionis's grants concentrate

Ionis Pharmaceuticals, Inc. is a focused PatentsView assignee: 15 CPC subclasses with 93.7% of grants classified under C12N (Microorganisms OR ENZYMES; Compositions THEREOF; Propagating, Preserving, OR Maintaining MICROORGANISMS; Mutation OR Genetic ENGINEERING; Culture Media). Peak complete grant year is 2017 (42 grants) versus a trough of 17 in 2024. By volume, Ionis sits between China University of Mining and Technology and Garmin Switzerland GmbH.

Ionis's three-year grant acceleration

From 2019–2021 to 2022–2024, Ionis Pharmaceuticals, Inc. moved from 93 to 75 grants (0.81x the prior three-year total, a multiple, not a CAGR). Among 3,296 tracked assignees with ≥100 grants and ≥20 prior-period grants, that multiple ranks #1,824. See the growth leaderboard.

China University…

272
Woodward

272
Central Glass

271
Fairchild Semicon…

271
Resonac

271
Techtronic Cordle…

271
Ionis Pharmaceuti… ◀

271
Colorado State Un…

270
Garmin Switzerland

270

What this shows Ionis holds 271 patents at rank #1,536, shown against the 8 assignees closest to it in grant volume rather than the industry's largest filers.

Companies ranked near Ionis

By rank, the assignees closest to #1,536 in granted patent volume.

Leaders in C12N (Microorganisms OR Enzymes)

Other assignees with the most granted patents in Ionis's primary technology class.

Assignees with similar portfolio profiles

Two PlainPatent-derived peer sets for Ionis, neither rank-band nor same-CPC leaders (those blocks stay above). In C12N (Microorganisms OR Enzymes), Ionis ranks #22 of 4,144 assignees by patent count in that subclass.

Similar innovation score

Nearest assignees by Innovation Score (52 here).

RingCentral, Inc. 52 Beijing Naura Microelectronics Equipment Co., Ltd. 52 Darex, LLC 52 Carl Zeiss AG 52

Similar claim depth

Nearest assignees by average claims per patent (22.9 here).

Takeda Vaccines, Inc. 22.9 avg Bioverativ Therapeutics Inc. 23.0 avg Location Labs, Inc. 23.0 avg Markforged, Inc 23.0 avg

Ionis's Innovation Score vs. every tracked assignee

Composite of portfolio volume, grant velocity, technology breadth, and claim depth (0–100)

52 Top 10% higher than 90% of 49,997 US assignees

Each bar is a band; taller bars hold more US assignees. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source USPTO PatentsView, PlainPatent Innovation Score · 2015–2025

USPTO utility patent grants by year · 2016–2025

Grants by year

Teal-shaded recent years (2020–present) versus the 2016–2019 baseline. Full figures in the table below.

View data table

Ionis Pharmaceuticals, Inc. patent grants by year, 2015–2025
Year	Patents Granted	Share of Period
2016	20	7.4%
2017	42	15.5%
2018	27	10.0%
2019	33	12.2%
2020	32	11.8%
2021	28	10.3%
2022	33	12.2%
2023	25	9.2%
2024	17	6.3%
2025partial year	14	5.2%

Which technologies does Ionis Pharmaceuticals, Inc. patent most?

C12N - Microorganisms OR ENZYMES; Compositions THEREOF; Propagating, Preserving, OR Maintaining MICROORGANISMS; Mutation OR Genetic ENGINEERING; Culture Media 254

A61P - Specific Therapeutic Activity OF Chemical Compounds OR Medicinal Preparations 160

A61K - Preparations FOR Medical, Dental OR Toiletry Purposes 140

C07H - SUGARS; Derivatives THEREOF; NUCLEOSIDES; NUCLEOTIDES; Nucleic Acids 84

C12Y - Enzymes 58

C07K - Peptides 16

C12Q - Measuring OR Testing Processes Involving Enzymes, Nucleic Acids OR Microorganisms ; Compositions OR Test Papers THEREFOR; Processes OF Preparing Such COMPOSITIONS; Condition-responsive Control IN Microbiological OR Enzymological Processes 9

G01N - Investigating OR Analysing Materials BY Determining Their Chemical OR Physical Properties 4

C07F - Acyclic, Carbocyclic OR Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium OR Tellurium 4

A61J - Containers Specially Adapted FOR Medical OR Pharmaceutical PURPOSES; Devices OR Methods Specially Adapted FOR Bringing Pharmaceutical Products Into Particular Physical OR Administering FORMS; Devices FOR Administering Food OR Medicines ORALLY; Baby COMFORTERS; Devices FOR Receiving Spittle 3

C12P - Fermentation OR Enzyme-using Processes TO Synthesise A Desired Chemical Compound OR Composition OR TO Separate Optical Isomers From A Racemic Mixture 3

C07D - Heterocyclic Compounds 2

Y10T - Technical Subjects Covered BY Former US Classification 1

Y02P - Climate Change Mitigation Technologies IN THE Production OR Processing OF Goods 1

A01K - Animal HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; Rearing OR Breeding Animals, NOT Otherwise Provided FOR; NEW Breeds OF Animals 1

Top 15 of 15 technology areas

More on this record

Data Source

USPTO PatentsView, US granted patents 2015–2025

View all rankings → How is Innovation Score calculated?

What to do with this data

Ionis Pharmaceuticals, Inc.'s patent record in context - here's where to go next.

Ionis Pharmaceuticals, Inc.'s lead technology class is C12N (Microorganisms OR ENZYMES; Compositions THEREOF; Propagating, Preserving, OR Maintaining MICROORGANISMS; Mutation OR Genetic ENGINEERING; Culture Media), 93.7% of its portfolio - see every assignee active in that class. Explore C12N
Ranked #1,536 of 49,997 tracked assignees by patent volume - see the full leaderboard. See the ranking
Compare Ionis Pharmaceuticals, Inc. against China University of Mining and Technology, an assignee filing at a similar volume. Compare portfolios
Innovation Score of 52.2/100 blends volume, velocity, technology breadth, and claim depth. How it's calculated

Figures reflect USPTO PatentsView grant data through May 2026; pending applications not yet granted are not counted.

Data sourced from USPTO PatentsView - official U.S. government patent data. See our methodology for computation details. Retrieved and formatted by PlainPatent

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the USPTO PatentsView database. Consult a qualified professional before making decisions based on this data.

Read our methodology - how this data is sourced, computed, and verified.

Data sources used on this page

USPTO PatentsView - the disambiguated bulk patent-grant, assignee, and CPC data this page's figures are derived from. patentsview.org
Cooperative Patent Classification (CPC) - the joint USPTO/EPO classification scheme used to group patents by technology area. cooperativepatentclassification.org
USPTO Patent Public Search - the official interface to verify the status of any individual patent. ppubs.uspto.gov

Compiled by PlainPatent , US Patent Intelligence Editorial Process · May 15, 2026

Every figure on PlainPatent is rendered directly from USPTO source data, no number is typed in by an editor. This page draws directly on USPTO source data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 2026.