Overall rank by patents
#1,536
Across all tracked assignees
USPTO 2015–2025 USPTO PatentsView US Corporation
Ionis Pharmaceuticals, Inc.
USPTO PatentsView assignee record — 271 granted patents across 15 technology areas, active 2016–2025. Filing-trend and competitive-moat analysis cross-referenced to USPTO Patent Public Search. Primary class: C12N (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA).
271
Total patents granted
15
CPC technology areas
22.9
Avg claims per patent
+22%
5-year filing velocity
Portfolio overview
Ionis Pharmaceuticals, Inc. has been granted 271 US utility patents between 2016 and 2025, placing Ionis Pharmaceuticals, Inc. at rank #1,536 across all assignees tracked by PlainPatent. This portfolio spans 15 distinct Cooperative Patent Classification (CPC) subclasses, averaging 22.9 claims per patent with primary concentration in C12N (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA). As a US Corporation, Ionis Pharmaceuticals, Inc. is one of the more focused assignees in the PatentsView dataset. The composite Innovation Score of 52.2/100 blends portfolio volume, filing velocity, technology breadth, and claim depth into a single comparable measure drawn directly from USPTO PatentsView records.
Filing cadence tells the strategic story. Between 2020 and 2025 the company received 149 grants, compared with 122 in the 2015–2019 window — a +22% shift in five-year velocity. Steady filing volume suggests sustained innovation without dramatic pivots. The US Corporation classification further shapes interpretation, since corporate, government, and individual filers pursue patents for materially different reasons.
Claim depth and technology breadth together indicate competitive posture. Ionis Pharmaceuticals, Inc.'s 22.9 average claims per patent reflects complex, broadly scoped inventions that are difficult for competitors to design around, while concentration in 15 subclasses points to a focused technical program. Combined with portfolio volume, these signals let analysts, investors, and licensing professionals benchmark Ionis Pharmaceuticals, Inc. against peers pursuing similar technology classes.
How does Ionis compare?
Granted US patents 2015–2025 versus the largest corporate holders — this company marked ◀
- Samsung
SAMSUNG ELECTRONICS CO., LTD.
106,890 patents
- International Bus…
International Business Machines Corporation
72,926 patents
- Canon 34,378
Canon Kabushiki Kaisha
34,378 patents
- LG 32,607
LG ELECTRONICS INC.
32,607 patents
- Taiwan Semiconduc… 31,041
TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.
31,041 patents
- Apple 30,560
Apple Inc.
30,560 patents
- Qualcomm Incorpor… 30,354
QUALCOMM Incorporated
30,354 patents
- Intel 27,498
Intel Corporation
27,498 patents
- Ionis Pharmaceuti… ◀ 271
Ionis Pharmaceuticals, Inc.
271 patents
What this shows Ionis holds 271 patents — placing it at rank #1,536 overall, well behind the volume leaders but ahead of the tens of thousands of smaller assignees in the dataset.
USPTO utility patent grants by year · 2016–2025
Grants by year
Teal-shaded recent years (2020–present) versus the 2016–2019 baseline. Full figures in the table below.
View data table
| Year | Patents Granted | Share of Period |
|---|---|---|
| 2016 | 20 | 7.4% |
| 2017 | 42 | 15.5% |
| 2018 | 27 | 10.0% |
| 2019 | 33 | 12.2% |
| 2020 | 32 | 11.8% |
| 2021 | 28 | 10.3% |
| 2022 | 33 | 12.2% |
| 2023 | 25 | 9.2% |
| 2024 | 17 | 6.3% |
| 2025 | 14 | 5.2% |
Which technologies does Ionis Pharmaceuticals, Inc. patent most?
Top 15 of 15 technology areas
Patent Moat Analysis
Portfolio Volume Moderate
Tech Breadth Focused
Claim Depth Complex
Velocity Growing
Frequently Asked Questions
How many patents does Ionis Pharmaceuticals, Inc. hold?
Ionis Pharmaceuticals, Inc. holds 271 US granted patents filed between 2016 and 2025, spanning 15 technology areas.
What is Ionis Pharmaceuticals, Inc.'s Innovation Score?
Ionis Pharmaceuticals, Inc. has an Innovation Score of 52.2 out of 100. This composite metric weighs portfolio volume (40%), filing velocity (20%), technology breadth (25%), and claim depth (15%).
What technology areas does Ionis Pharmaceuticals, Inc. focus on?
Ionis Pharmaceuticals, Inc.'s top technology area is C12N (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA) with 254 patents. The company has filed patents in 15 CPC subclasses total.
Is Ionis Pharmaceuticals, Inc.'s patent filing rate increasing or decreasing?
Ionis Pharmaceuticals, Inc.'s recent filing velocity is +22% compared to the prior five-year period. The company is maintaining or growing its patent output.
What does claim depth mean for Ionis Pharmaceuticals, Inc.'s patents?
Ionis Pharmaceuticals, Inc.'s patents average 22.9 claims each. This indicates complex, broadly scoped patents that are harder for competitors to design around.
How is the Ionis Pharmaceuticals, Inc. patent data sourced?
All patent data comes from USPTO PatentsView, a public research dataset maintained by the United States Patent and Trademark Office covering US granted utility patents from 2015 to 2025.
Learn More
Explore the patent dataset
C12N technology
Ionis Pharmaceuticals, Inc.'s primary CPC class — all holders and yearly trends
Top 50 patent holders
See where Ionis Pharmaceuticals, Inc. ranks among the largest US patent assignees
All technology classes
Browse every CPC technology area by patent activity
How the score works
The four dimensions behind the Innovation Score
Related
Data sourced from USPTO PatentsView — official U.S. government patent data. See our methodology for computation details. Retrieved and formatted by PlainPatent Editorial
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the USPTO PatentsView database. Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
All federal data sources used on this page
- USPTO PatentsView — official U.S. Patent and Trademark Office bulk patent data. patentsview.org
- USPTO Patent Application Information Retrieval (PAIR) — application status and file history. uspto.gov/patents/pair
- USPTO Bulk Data Storage System — comprehensive patent text + claims dataset. bulkdata.uspto.gov
- USPTO CPC Classification — Cooperative Patent Classification scheme for technology categorization. uspto.gov/cpc
- SEC EDGAR — public filings cross-reference for assignee corporate entity matching. sec.gov/edgar
- WIPO PATENTSCOPE — international patent context (related international filings). wipo.int/patentscope
