CPC technology class · G16
G16B — Bioinformatics
Bioinformatics, i.e. information and communication technology [ict] specially adapted for genetic or protein-related data processing in computational molecular biology. 6,310 US utility patents granted 2015–2025, with the leading assignees and year-by-year filing trajectory.
- 6,310
- US patents granted
- G16
- Parent CPC class
- 20
- Active assignees
- +91%
- 5-yr velocity
CPC subclass G16B — BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY — covers 6,310 US utility patents granted between 2015 and 2025 according to USPTO PatentsView records. This subclass sits within the broader CPC class G16 (INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS), one of roughly 250 top-level technology categories in the Cooperative Patent Classification system jointly maintained by the USPTO and the European Patent Office. At the subclass level, four-character codes like G16B give the most practical resolution for tracking a specific technology domain without losing sight of adjacent filings. Every grant here has been classified by a USPTO examiner based on the technical disclosure in the patent specification.
The competitive landscape in G16B is shaped by 20 distinct companies actively filing in this space. International Business Machines Corporation leads with 144 patents, followed by Life Technologies Corporation at 1,296 grants and Immatics Biotechnologies GmbH at 690. Concentration at the top of the leaderboard indicates whether this technology area is dominated by a handful of incumbents or fragmented across many filers — a useful signal for investors evaluating competitive moats and for product teams mapping freedom-to-operate risk.
Filing trajectory matters as much as static counts. The yearly series on this page plots grants from 2015 through 2025, highlighting whether innovation in G16B is accelerating, plateauing, or cooling. Technology areas with rising post-2020 activity often reflect emerging markets or new platform shifts, while declining filings can signal mature domains where incremental improvement has slowed. Researchers, licensing professionals, and competitive-intelligence teams use these patterns — together with the top-assignee distribution — to decide where to invest, where to license, and where to avoid entanglement. All counts on this page come directly from USPTO PatentsView and reflect US granted utility patents only.
Is G16B innovation accelerating?
US utility-patent grants per year in G16B, 2015–2025 — recent five years are up 91% versus 2015–2019.
Who leads G16B?
The 12 most active assignees in BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY — wider bars mean more grants
- Illumina 890
Illumina, Inc.
890 patents
- Life
Life Technologies Corporation
1,296 patents
- Immatics Biotechnolog… 690
Immatics Biotechnologies GmbH
690 patents
- Guardant Health 120
Guardant Health, Inc.
120 patents
- The Board of Trustees…
The Board of Trustees of the Leland Stanford Junior University
2,275 patents
- Heartflow 285
Heartflow, Inc.
285 patents
- 23andme 107
23andMe, Inc.
107 patents
- The Chinese Universit… 307
The Chinese University of Hong Kong
307 patents
- Seven Bridges Genomics 65
Seven Bridges Genomics Inc.
65 patents
- ubiome 59
uBiome, Inc.
59 patents
- Natera 122
Natera, Inc.
122 patents
- The Broad Institute 410
The Broad Institute, Inc.
410 patents
What this shows International Busines… is the most active filer in G16B, holding 144 of the 6,310 patents in this class. Concentration at the top signals how contestable this technology area is for new entrants.
View data table
| Rank | Company | Patents in G16B |
|---|---|---|
| #1 | Illumina, Inc. | 890 |
| #2 | Life Technologies Corporation | 1,296 |
| #3 | Immatics Biotechnologies GmbH | 690 |
| #4 | Guardant Health, Inc. | 120 |
| #5 | The Board of Trustees of the Leland Stanford Junior University | 2,275 |
| #6 | Heartflow, Inc. | 285 |
| #7 | 23andMe, Inc. | 107 |
| #8 | The Chinese University of Hong Kong | 307 |
| #9 | Seven Bridges Genomics Inc. | 65 |
| #10 | uBiome, Inc. | 59 |
| #11 | Natera, Inc. | 122 |
| #12 | The Broad Institute, Inc. | 410 |
| #13 | Sequenom, Inc. | 73 |
| #14 | Nant Holdings IP, LLC | 476 |
| #15 | 10x Genomics, Inc. | 373 |
| #16 | KPN INNOVATIONS LLC | 231 |
| #17 | Ancestry.com DNA, LLC | 56 |
| #18 | GRAIL, INC. | 55 |
| #19 | Personalis, Inc. | 38 |
| #20 | VERINATA HEALTH, INC. | 48 |
About This Class
CPC subclass G16B belongs to class G16.
6,310 patents were granted in this class between 2015 and 2025.
20 companies actively patent in this space.
Classification System
Cooperative Patent Classification (CPC) is a hierarchical patent classification system used by the USPTO and EPO.
Frequently Asked Questions
What is CPC class G16B?
How many patents have been filed in G16B?
Which company holds the most patents in G16B?
How is patent data for G16B collected?
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Read our methodology — how this data is sourced, computed, and verified.