CPC technology class · C40
C40B — Combinatorial Chemistry
Combinatorial chemistry; libraries, e.g. chemical libraries. 2,284 US utility patents granted 2015–2025, with the leading assignees and year-by-year filing trajectory.
- 2,284
- US patents granted
- C40
- Parent CPC class
- 20
- Active assignees
- +54%
- 5-yr velocity
CPC subclass C40B — COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES — covers 2,284 US utility patents granted between 2015 and 2025 according to USPTO PatentsView records. This subclass sits within the broader CPC class C40 (COMBINATORIAL TECHNOLOGY), one of roughly 250 top-level technology categories in the Cooperative Patent Classification system jointly maintained by the USPTO and the European Patent Office. At the subclass level, four-character codes like C40B give the most practical resolution for tracking a specific technology domain without losing sight of adjacent filings. Every grant here has been classified by a USPTO examiner based on the technical disclosure in the patent specification.
The competitive landscape in C40B is shaped by 20 distinct companies actively filing in this space. President and Fellows of Harvard College leads with 60 patents, followed by Prognosys Biosciences, Inc. at 73 grants and Inscripta Inc. at 165. Concentration at the top of the leaderboard indicates whether this technology area is dominated by a handful of incumbents or fragmented across many filers — a useful signal for investors evaluating competitive moats and for product teams mapping freedom-to-operate risk.
Filing trajectory matters as much as static counts. The yearly series on this page plots grants from 2015 through 2025, highlighting whether innovation in C40B is accelerating, plateauing, or cooling. Technology areas with rising post-2020 activity often reflect emerging markets or new platform shifts, while declining filings can signal mature domains where incremental improvement has slowed. Researchers, licensing professionals, and competitive-intelligence teams use these patterns — together with the top-assignee distribution — to decide where to invest, where to license, and where to avoid entanglement. All counts on this page come directly from USPTO PatentsView and reflect US granted utility patents only.
Is C40B innovation accelerating?
US utility-patent grants per year in C40B, 2015–2025 — recent five years are up 54% versus 2015–2019.
Who leads C40B?
The 12 most active assignees in COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES — wider bars mean more grants
- Illumina
Illumina, Inc.
890 patents
- Prognosys Biosciences 73
Prognosys Biosciences, Inc.
73 patents
- Inscripta 165
Inscripta Inc.
165 patents
- 10x Genomics 373
10x Genomics, Inc.
373 patents
- University of Washing…
University of Washington
691 patents
- Twist Bioscience 65
Twist Bioscience Corporation
65 patents
- Illumina Cambridge 253
Illumina Cambridge Limited
253 patents
- Bio-rad Laboratories
Bio-Rad Laboratories, Inc.
597 patents
- Dyax 55
Dyax Corp.
55 patents
- Bristol-myers Squibb
Bristol-Myers Squibb Company
1,089 patents
- Gigagen 21
GigaGen, Inc.
21 patents
- Roche Sequencing Solu… 273
Roche Sequencing Solutions, Inc.
273 patents
What this shows President and Fellows… is the most active filer in C40B, holding 60 of the 2,284 patents in this class. Concentration at the top signals how contestable this technology area is for new entrants.
View data table
| Rank | Company | Patents in C40B |
|---|---|---|
| #1 | Illumina, Inc. | 890 |
| #2 | Prognosys Biosciences, Inc. | 73 |
| #3 | Inscripta Inc. | 165 |
| #4 | 10x Genomics, Inc. | 373 |
| #5 | University of Washington | 691 |
| #6 | Twist Bioscience Corporation | 65 |
| #7 | Illumina Cambridge Limited | 253 |
| #8 | Bio-Rad Laboratories, Inc. | 597 |
| #9 | Dyax Corp. | 55 |
| #10 | Bristol-Myers Squibb Company | 1,089 |
| #11 | GigaGen, Inc. | 21 |
| #12 | Roche Sequencing Solutions, Inc. | 273 |
| #13 | Vibrant Holdings, LLC | 56 |
| #14 | Adimab, LLC | 45 |
| #15 | ENZO LIFE SCIENCES, INC. | 55 |
| #16 | CHUGAI SEIYAKU KABUSHIKI KAISHA | 325 |
| #17 | BioAtla, Inc. | 43 |
| #18 | NUEVOLUTION A/S | 25 |
| #19 | The Broad Institute, Inc. | 410 |
| #20 | THE SCRIPPS RESEARCH INSTITUTE | 400 |
About This Class
CPC subclass C40B belongs to class C40.
2,284 patents were granted in this class between 2015 and 2025.
20 companies actively patent in this space.
Classification System
Cooperative Patent Classification (CPC) is a hierarchical patent classification system used by the USPTO and EPO.
Frequently Asked Questions
What is CPC class C40B?
How many patents have been filed in C40B?
Which company holds the most patents in C40B?
How is patent data for C40B collected?
What is the difference between CPC class and subclass?
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Explore the patent dataset
Read our methodology — how this data is sourced, computed, and verified.